Ultraviolet absorption spectra are recorded of cis‐ and trans‐ cinnamic acid, of cis‐ and trans‐1,2,3,4,‐tetrahydronaphthylidene (1) acetic acid and of cis‐ and trans‐β‐(naphthyl‐1) acrylic acid.The cis isomers all show a lower extinction coefficient and a shift of the maximum of absorption to shorter wave‐length in comparison with the trans isomers. Cinnamic acid is a white crystalline compound this is slightly soluble in water, or freely soluble in many organic solvents. cis-ferulic acid (CHEBI:76117) has functional parent cis-cinnamic acid (CHEBI:35699) cis-cinnamate (CHEBI:35700) is conjugate base of cis-cinnamic acid (CHEBI:35699) IUPAC Name (2 Z )-3-phenylprop-2-enoic acid The couples of compounds differed for the kind of aromatic substitution (p-hydroxy, p-hydroxymethoxy, p-hydroxydimethoxy, dihydroxy). Indeed, CA hydroxy-derivatives (hydroxycinnamic acids, … Cinnamic acid is a white crystalline compound this is slightly soluble in … 25 matches found for trans-cinnamic acid Advanced Search | Structure Search Sort By Relevance Name ↑ Name ↓ Base Name ↑ Base Name ↓ Formula Weight ↑ Formula Weight ↓ Cinnamic acid (3‐phenylprop‐2‐enoic acid, 3‐phenylacrylic acid, Fig. The CINNAMIC ACID molecule shown in the visualization screen can be rotated interactively by keep clicking and moving the mouse button. Cinnamic acid (CA) and its hydroxy-derivatives are aromatic building blocks whose structural peculiarities (unsaturation, hydroxylic and/or carboxylic groups) have driven them to a prominent position in polymer science. 5 / 14. For a better understanding of the chemical structure, an interactive 3D visualization of CINNAMIC ACID is provided here. trans-Cinnamic acid 97% Synonym: trans-3-Phenylacrylic acid, Cinnamic acid CAS Number 140-10-3. 5 / 14. CopyCopied, Validated by Experts, Validated by Users, Non-Validated, Removed by Users, Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, Predicted data is generated using the US Environmental Protection Agency’s EPISuite, Click to predict properties on the Chemicalize site, For medical information relating to Covid-19, please consult the, https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:27386, https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:35697, ACD/Labs Percepta Platform - PhysChem Module, US Environmental Protection Agency’s EPISuite, Compounds with the same molecular formula, Search Google for structures with same skeleton, 147 deg C / 4 mm (350.4434 °C / 760 mmHg). These molecules are visualized, downloaded, and analyzed by users who range from students to specialized scientists. 106.12 g of Benzaldehyde yields Cinnamic Acid = 148.16 g. 10.5 g of Benzaldehyde shall yield Cinnamic Acid = 148. Fluorimetric studies on the binding of 4-(dimethylamino)cinnamic acid with micelles and bovine serum albumin. Cinnamic acid exists as trans and cis isomers, but the trans form is the one most often found in nature and is the article of commerce. Heat of Vaporization at Normal Boiling Point, LogP (Octanol-Water Partition Coefficient), Ghose-Crippen Octanol-Water Partition Coefficient (logP), Moriguchi Octanol-Water Partition Coefficient (logP), Activity Score for Ion Channel Modulators, Activity Score for Nuclear Receptor Ligands, Structure Data File (SDF/MOL File) of CINNAMIC ACID, download in the SDF page of CINNAMIC ACID, InChI=1S/C9H8O2/c10-9(11)7-6-8-4-2-1-3-5-8/h1-7H,(H,10,11)/b7-6+, 19 atom(s) - 8 Hydrogen atom(s), 9 Carbon atom(s) and 2 Oxygen atom(s), 19 bond(s) - 11 non-H bond(s), 8 multiple bond(s), 2 rotatable bond(s), 2 double bond(s), 6 aromatic bond(s), 1 six-membered ring(s), 1 carboxylic acid(s) (aliphatic) and 1 hydroxyl group(s), Cinnamic acid, United States Pharmacopeia (USP) Reference Standard, trans-Cinnamic acid, natural, >=99%, FCC, FG. 2008 Sep;7(9):1063-70. trans-Cinnamic acid ≥99% Synonym: trans-3-Phenylacrylic acid, Cinnamic acid CAS Number 140-10-3. Stable. You can also browse global suppliers,vendor,prices,Price,manufacturers of trans-Cinnamic acid(140-10-3). α-Cyano-4-hydroxycinnamic acid; Caffeic acid – burdock, hawthorn, artichoke, pear, basil, thyme, oregano, apple The crystal structures of p-chloro-trans-cinnamic acid (I) and β-(p-chlorophenyl) propionic acid (II) have been determined from X-ray diffractometer data. Organic Compound; Ester; Food Toxin; Plant Toxin; Metabolite; Household Toxin; Natural Compound, ORL-RAT LD50 2500 mg kg-1, IPR-RAT LD50 1600 mg kg-1, ORL-MUS LD50 5000 mg kg-1, IPR-MUS LD50 160 mg kg-1, P261; P280; P302+P352; P304+P340; P305+P351+P338; P312, WARNING: Irritates skin and eyes, harmful if swallowed. A chemical structure of a molecule includes the arrangement of atoms and the chemical bonds that hold the atoms together. Learn more at http://www.doceri.com The carbon atoms in the chemical structure of CINNAMIC ACID are implied to be located at the corner(s) and hydrogen atoms attached to carbon atoms are not indicated – each carbon atom is considered to be associated with enough hydrogen atoms to provide the carbon atom with four bonds. It is a conjugate acid of a cinnamate. 1b), cinnamyl alcohol (Fig. Sorry this one is long. Structure Identification: Photochem Photobiol Sci. Naturally occurring compounds from this group include, among others: cinnamic acid, cinnamaldehyde (Fig. The molecular structure is based on structures generated from information available in ECHA’s databases. Attention was focused on the antifungal activities exhibited against Aspergillus flavus, Aspergillus terreus, and Aspergillus niger. 16 / 106. EC Number 205-398-1. At last,trans-Cinnamic acid… It is a white crystalline compound that is slightly soluble in water, and freely soluble in many organic solvents. IUPAC names (2E)-3-phenylprop-2-enoic acid . The kinetic behavior of cinnamic acids, their methyl esters, and two catechols 1−10 (ArOH) in the reaction with DPPH• in methanol and ethanol is not compatible with a reaction mechanism that involves hydrogen atom abstraction from the hydroxyl group of 1−10 by DPPH•. Hydroxycinnamic acids (hydroxycinnamates) are a class of aromatic acids or phenylpropanoids having a C 6 –C 3 skeleton. Almost all of the compounds showed some inhibition activity on each of the fungi at 0.5 mM. The molecular weight of CINNAMIC ACID is available in molecular weight page of CINNAMIC ACID, which is calculated as the sum of the atomic weights of each constituent element multiplied by the number of atoms of that element in the molecular formula. The RCSB PDB also provides a variety of tools and resources. 2020-12-26. Identification Product Name trans-Cinnamic acid Cat No. ... cinnamic acid . It is a crystalline compound that is white in colour and is slightly soluble in water. Then, try SnaPeaks – simply upload your MS/MS data and SnaPeaks will provide what’s in your natural products. Pre-Registration process . Doceri is free in the iTunes app store. The antioxidant activity of four derivatives of benzoic acid was systematically compared with the activity of the four homologous derivatives of cinnamic acid. MDL number MFCD00004369. CGAs are ubiquitous in the plant kingdom, produced by nearly all plant species in variable amounts and with variable structures. A series of cinnamic acid derivatives, amides (1-12) and esters (13-22), were synthesized, and structure-activity relationships for antioxidant activity, and monoamine oxidases (MAO) A and B, acetylcholinesterase, and butyrylcholinesterase (BChE) inhibitory activities were analyzed. trans-Cinnamic acid is a sweet, balsam, and cinnamon tasting compound. Articles of trans-Cinnamic acid are included as well. trans-Cinnamic acid exists in all living species, ranging from bacteria to humans. 621-82-9 - WBYWAXJHAXSJNI-UHFFFAOYSA-N - Cinnamic acid - Similar structures search, synonyms, formulas, resource links, and other chemical information. Title:Cinnamic Acid Derivatives as Inhibitors of Oncogenic Protein Kinases – Structure, Mechanisms and Biomedical Effects# VOLUME: 23 ISSUE: 10. This video screencast was created with Doceri on an iPad. The information of the atoms, bonds, connectivity and coordinates included in the chemical structure of CINNAMIC ACID can easily be identified by this visualization. Classified as an unsaturated carboxylic acid, it occurs naturally in a number of plants.It exists as both a cis and a trans isomer, although the latter is more common. CopyCopied, CSID:392447, http://www.chemspider.com/Chemical-Structure.392447.html (accessed 23:29, Jan 8, 2021)
It is obtained from cinnamon bark and balsam resins such as storax. trans-Cinnamic acid is a weakly acidic compound (based on its pKa). The cinnamic acid is soluble in dichloromethane at room temperature and thus before the bromine addition the reaction vessel holds a colourless solution. Author(s):Marcin Mielecki and Bogdan Lesyng. Cinnamic acid is a naturally occurring aromatic acid and is considered to be safe for human consumption. The CINNAMIC ACID molecule contains a total of 19 bond(s) There are 11 non-H bond(s), 8 multiple bond(s), 2 rotatable bond(s), 2 double bond(s), 6 aromatic bond(s), 1 six-membered ring(s), 1 carboxylic acid(s) (aliphatic) and 1 hydroxyl group(s). 1999 Apr;47(4) :1453-9. Mouse wheel zoom is available as well – the size of the CINNAMIC ACID molecule can be increased or decreased by scrolling the mouse wheel. MDL number MFCD00004369. Cinnamic acid. It is a member of styrenes and a member of cinnamic acids. It was first isolated in 1872 by F. Beilstein (of Handbook of Organic Chemistry fame) and A. Kuhlberg. Incompatible with strong oxidizing agents. Syntheses of the cis-cinnamic acid analogues 4–8: (a) ethyl 2-[bis(2-isopropylphenoxy)phosphoryl]acetate, Triton B, THF, −78 °C, 94%, Z:E = 98:2, (b) 10% NaOH aq., EtOH, rt, 97%, (c) MOMCl, diisopropylethylamine, 0 °C, 99%, (d) 2-cyanoethanol, EDCI, DMAP, CH 2 Cl 2, 0 °C, 91%, Z:E = 63:37, (e) (COCl) 2, DMF (1 drop), CH 2 Cl 2, 0 °C, (f) 28% NH 4 OH aq., CH 2 Cl 2, 0 °C, … : A13538 CAS-No 140-10-3 Synonyms 3-Phenyl-2-propenoic acid; trans-3-Phenylacrylic acid Recommended Use Laboratory chemicals. Abstract The bromination of trans-cinnamic acid was completed to determine dibromide’s stereochemical structure and its mechanism. Chemical structure: This structure is also available as a 2d Mol file or as a computed 3d SD file The 3d structure may be viewed using Java or Javascript. Data compiled as indicated in comments: ALS - Hussein Y. Afeefy, Joel F. Liebman, and Stephen E. Stein DH- Eugene S. Domalski and Elizabeth D. Hearing As a member of the wwPDB, the RCSB PDB curates and annotates PDB data according to agreed upon standards. Structure−activity relationship was derived also. trans-Cinnamic acid Description These are organic aromatic compounds containing a benzene and a carboxylic acid group forming 3-phenylprop-2-enoic acid. Trans-3-phenyl-2-propenoic acid (cinnamic acid) derivatives: structure-activity relationship as hepatoprotective agents Medicinal chemistry (Shāriqah (United Arab Emirates)), 2007 Rosa Bobadilla 5 = 14.66 g. Hence, Theoretical yield of Cinnamic Acid = 14.66 g. If reported Practical yield = 9.5 g. Then, Percentage Practical yield = Practical yield / Theoretical yield × 100 = 9. EC Number 205-398-1. Cinnamic acid is an organic compound with the formula C6H5CH=CHCOOH. The antioxidant activity of four derivatives of benzoic acid was systematically compared with the activity of the four homologous derivatives of cinnamic acid. Stereoisomers: (Z)-3-Phenyl-2-propenoic acid; 2-Propenoic acid, 3-phenyl- Doceri is free in the iTunes app store. Visit ChemicalBook To find more trans-Cinnamic acid(140-10-3) information like chemical properties,Structure,melting point,boiling point,density,molecular formula,molecular weight, physical properties,toxicity information,customs codes. In our definition, CGAs are all hydroxycinnamate esters of (−)-quinic acid. A monocarboxylic acid that consists of acrylic acid bearing a phenyl substituent at the 3-position. 709
Chemsrc provides trans-Cinnamic acid(CAS#:140-10-3) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. … The electronic absorption spectra of cinnamic acid and some cinnamoyl azides have been recorded in absolute methanol and investigated to explore the structure of the titled compounds. Molecular Weight 148.16 . It is a white crystalline compound that is slightly soluble in water, and freely soluble in … This video screencast was created with Doceri on an iPad. Linear Formula C 6 H 5 CH=CHCOOH . trans-Cinnamic acid. trans-Cinnamic acid is a sweet, balsam, and cinnamon tasting compound. 140-10-3 - WBYWAXJHAXSJNI-VOTSOKGWSA-N - Cinnamic acid - Similar structures search, synonyms, formulas, resource links, and other chemical information. Differential scanning calorimetry showed that 1 undergoes a single fully reversible temperature induced phase transition at around 132/131 K (cooling/heating). Cinnamic acid is a monocarboxylic acid that consists of acrylic acid bearing a phenyl substituent at the 3-position. The first step has multiple possibilities. It is collected from the oil of cinnamon and is also found in shea butter. Shea, research. The first step has multiple possibilities. Please hyperlink "Mol-Instincts" to www.molinstincts.com. Bromination of Cinnamic acid Supplementary Material Experimental notes This experiment aims at the preparation of the 2,3-dibromo-3-phenylpropanoic acid from cinnamic acid by bromine addition. Linear Formula C 6 H 5 CH=CHCOOH . Title:Cinnamic Acid Derivatives as Inhibitors of Oncogenic Protein Kinases – Structure, Mechanisms and Biomedical Effects# VOLUME: 23 ISSUE: 10. The
E (
trans) isomer of cinnamic acid. A structure-antifungal activity relationship (SAR) study of 22 related cinnamic acid derivatives was carried out. It has a role as a plant metabolite. (E)-3-(4-methoxy-3-(3-methylbut-2-enyl)phenyl)acrylic … In this study, we study the effect of the ethanol extract of C. cassia (CCE) and its active compound CA, on angiogenic processes in in vitro and in vivo. Images of the chemical structure of CINNAMIC ACID are given below: The 2D chemical structure image of CINNAMIC ACID is also called skeletal formula, which is the standard notation for organic molecules. The full spectrum can only be viewed using a FREE account. Visit ChemicalBook To find more trans-Cinnamic acid(140-10-3) information like chemical properties,Structure,melting point,boiling point,density,molecular formula,molecular weight, physical properties,toxicity information,customs codes. Molecular Formula C 9 H 8 O 2; Average mass 148.159 Da; Monoisotopic mass 148.052429 Da; ChemSpider ID 392447 (E)-3-(4-methoxy-3-(3-methylbut-2-enyl)phenyl)acrylic … The 3D chemical structure image of CINNAMIC ACID is based on the ball-and-stick model which displays both the three-dimensional position of the atoms and the bonds between them. The cinnamic acid is soluble in dichloromethane at room temperature and thus before the bromine addition the reaction vessel holds a colourless solution. The observed fundamental frequencies (IR and Raman) were assigned according to their trans-Cinnamic acid Description These are organic aromatic compounds containing a benzene and a carboxylic acid group forming 3-phenylprop-2-enoic acid. Go To: Top, Phase change data, Mass spectrum (electron ionization), References, Notes Data compilation copyrightby the U.S. Secretary of Commerce on behalf of the U.S.A.All rights reserved. Conversion of complicated chemical-related units is no longer sophisticated with the aid of UnitPot. For physicochemical, thermodynamic, transport, spectra, and other property data & information, the followings are available from “Mol-Instincts”, a chemical database based on quantum mechanics: The SMILES string of CINNAMIC ACID is OC(=O)C=Cc1ccccc1, which can be can be imported by most molecule editors for conversion back into two-dimensional drawings or three-dimensional models of the CINNAMIC ACID. These compounds are hydroxy derivatives of cinnamic acid.. Source: Mol-Instincts Chemical Database, Predicted on Quantum. A series of cinnamic acid esters and their derivatives were synthesized and evaluated for antifungal activities in vitro against four plant pathogenic fungi by using the mycelium growth rate method. Chemical structure: This structure is also available as a 2d Mol file or as a computed 3d SD file The 3d structure may be viewed using Java or Javascript. Articles of trans-Cinnamic acid are included as well. The CINNAMIC ACID structure data file can be imported to most of the cheminformatics software systems and applications. The crystal structure of trans-4-(trifluoromethyl) cinnamic acid (1) has been determined in the triclinic space groupP. 1c), 4‐hydroxycinnamic acid (p‐coumaric acid, Fig. Therefore, in this study, the antibacterial activity of trans ‐cinnamic acid and commonly used antibiotics, namely chloramphenicol, vancomycin, streptomycin and erythromycin, were tested against 32 bacteria, including fish pathogens, nonpathogenic isolates and collection strains. Details of the supplier of the safety data sheet Cis-cinnamic acid is the Z (cis) isomer of cinnamic acid It is a conjugate acid of a cis-cinnamate. Stereoisomers: (Z)-3-Phenyl-2-propenoic acid; 2-Propenoic acid, 3-phenyl- After the addition of bromine to trans-cinnamic acid, the product was identified by its melting point and infrared spectrum resulting in erythro-2,3-Dibromo-3-phenylpropanoic acid after comparing similar properties.